Recipe By Mark Adams
Published Oct 7th
Pizza Spaghetti Casserole
Prep 20m Cook 50m Additional - Ready In 1h 10m
Servings 8 servings Calories 581.8

Freakin’ delicious! Add any extra pizza toppings (black olives, sausage, onions, green peppers, etc.) if desired.

Recipe Ingredients

  • 1 (16 ounce) package spaghetti
  • 1 pound ground beef
  • ½ cup milk
  • 1 egg
  • 1 (26 ounce) jar pasta sauce
  • 1 (16 ounce) can diced Italian-style tomatoes
  • ½ teaspoon garlic powder
  • ½ teaspoon dried oregano
  • 2 ounces sliced pepperoni, divided
  • 1 (8 ounce) package shredded Italian cheese blend
  • ¼ cup grated Parmesan cheese

Cooking Directions

  1. 1 Preheat oven to 350 degrees F (175 degrees C). Grease a 9x13-inch baking dish.
  2. 2 Bring a large pot of lightly salted water to a boil. Cook spaghetti in the boiling water, stirring occasionally, until cooked through but firm to the bite, about 12 minutes. Drain water and transfer spaghetti to the prepared baking dish.
  3. 3 Heat a large skillet over medium-high heat. Cook and stir beef in the hot skillet until browned and crumbly, 5 to 7 minutes; drain and discard grease.
  4. 4 Whisk milk and egg together in a bowl; pour over spaghetti. Add pasta sauce, diced tomatoes, garlic powder, and oregano to spaghetti and mix well.
  5. 5 Spread ground beef over spaghetti mixture and top with 1/2 of the pepperoni. Sprinkle Italian cheese blend over pepperoni and top with the remaining pepperoni and Parmesan cheese.
  6. 6 Bake in the preheated oven until cheese is browned and bubbling, about 30 minutes.

Nutrition Facts

  • Calories 581.8
  • Carbohydrate 59.8 g
  • Cholesterol 91.4 mg
  • Fat 24.3 g
  • Fiber 4.7 g
  • Protein 28.9 g
  • Saturated Fat 10.8 g
  • Sodium 935.2 mg
  • Sugar 10.4 g


  1. I wanted to get a pic posted for this dish. It was super easy to make. My kids and I loved it. Enough food for ten people if need be. Mixing it all up was key.
  2. its not my favorite taste
  3. my husbands first comment was "This is a Keeper"...I'll be making this again! I did not add the canned tomatoes just due to personal preference but added more spaghetti sauce so it wouldn't be dry. I also added mushrooms to the good...thanks for an easy tasty recipe
  4. This freezes great for later use. I double the recipe and it makes three 8x8 pans. I always make more spaghetti than the recipe calls for. I use fresh garlic onions green pepper and cook with the hamburger. I add the sauce to it after that with seasonings and simmer while I cook spaghetti. Once - Read more ...
  5. the recipe was not as good as I thought it was gonna be. I did like the ground beef cheese and pepperoni on top. that to me was the best part.
  6. Very good. Made just a couple changes. Used Italian sausage instead of hamburger. Also used macaroni noodles based on other reviews. Lastly used half pizza sauce and half spaghetti sauce. I mixed everything together vs layering it. Turned out great
  7. I added mushrooms to it as well since we like them and it turned out great! Cooked them in with the hamburger meat once it was almost done.
  8. I thought this was okay. I also got 8 servings but 582 calories per serving is crazy high. I was able to bring it down to 415 but still not a lite dish obviously. I used all reduced fat dairy products leaner beef and turkey pepperoni. I also sautéed green pepper onion and mushrooms (per - Read more ...
  9. We enjoyed this and we'll make it again. I used 12 oz of spagetti a cheesy rosa sauce and spicy pork sausage in place of ground beef. I mixed the meat in with the noodles instead of layering it. Next time we'll add minced garlic onions and black olives and try a different kind of - Read more ...
  10. I was looking for a way to use up my ground beef. This recipe came up, no comments, no pictures. I figured I'd give it a try anyway. We really like it. The only thing I changed is I used rotini pasta instead of spaghetti to make it easier to scoop out of the dish. - Read more ...